Skin-Identical Skincare · One Cream, Every Night
Our Science

Skin Science,
Re-engineered.

SEISUI combines vitamin A, a skin-like membrane, barrier lipids, antioxidants, a peptide and several hydrating ingredients in one formula. At its foundation is a membrane of phospholipids and barrier lipids, built in layers like your skin's own barrier. Everything else was built around it, so one cream can renew, strengthen and hydrate the skin at the same time.

One cream. Many ingredients. One system.

Champagne-toned phospholipid bilayer diagram with an aqueous core, hydrophilic heads and hydrophobic tails
01DMS Membrane Technology

A Membrane,
Not Just a Cream.

What makes SEISUI different is its structure. It uses a Derma Membrane Structure (DMS), built from Hydrogenated Phosphatidylcholine, Phosphatidylcholine and Hydrogenated Lecithin. With other skin-friendly lipids, they form thin, stacked layers, much like the layers of your skin barrier.

To this membrane, SEISUI adds five ceramides, cholesterol and phytosphingosine, the key lipids of the skin barrier. The result is a cream organised like skin, instead of a layer of oil sitting on top of it.

The structure is the technology.

Annotated phospholipid bilayer showing membrane proteins, cholesterol, glycolipids, hydrophilic heads and hydrophobic tails
Water droplets beading on the surface of a broad green leaf
02The Skin Barrier

Five Ceramides.
Cholesterol.
Phytosphingosine.

Your skin barrier is made of lipids arranged in an ordered way. SEISUI contains five ceramides (NP, AP, AS, NG and EOP) together with cholesterol and phytosphingosine, so it supports the whole lipid system, not just one part of it.

These ingredients help the barrier hold on to moisture and stay supple. For you, the benefit is simple: skin that feels more comfortable and hydrated, and looks smoother, plumper and healthier.

03Retinal
Up to11×

Faster Than
Standard Retinol.

Retinaldehyde, or retinal, is one of the most advanced forms of vitamin A in skincare, just one metabolic step from retinoic acid. Clinical research shows improvements in wrinkles, texture and hydration with good tolerability. Unlike retinol and retinoic acid, it also has antibacterial activity against blemish-causing bacteria.

Retinal is reported to act up to 11× faster than standard retinol, while being better tolerated than prescription retinoic acid. SEISUI encapsulates it for stability, protects it in an airless pump, and surrounds it with a membrane-based barrier system, ceramides, cholesterol and ectoin.

Powerful renewal, with barrier support built in.

Close-up of a woman's face crossed by a soft band of prismatic light
Annotated molecular illustration of Ascorbyl Tetraisopalmitate showing its vitamin C core, lipophilic chains and stable ester linkage
04Advanced Vitamin C

Ascorbyl
Tetraisopalmitate.
Lipid-Soluble Vitamin C.

SEISUI uses Ascorbyl Tetraisopalmitate, an oil-soluble form of vitamin C. Because it dissolves in oil, it works well in SEISUI's lipid-rich formula.

Vitamin C is an antioxidant that supports firm-looking skin and a more even tone, and is valued for a brighter, more radiant complexion. SEISUI pairs it with vitamin E, EGCG and rosemary extract for broader antioxidant protection.

Ascorbyl Tetraisopalmitate · Tocopherol · EGCG · Rosemary Extract

05The Peptide

Palmitoyl Pentapeptide-4.
Precision Anti-Ageing Support.

SEISUI contains Palmitoyl Pentapeptide-4, a peptide linked to a fatty acid and developed for anti-ageing skincare. Peptides like this have been studied for their effect on wrinkles and skin texture.

In SEISUI, it works alongside retinal, niacinamide, vitamins C and E and the antioxidants, so several ingredients target signs of ageing at once. The goal: smoother-looking skin, refined texture and a more youthful look.

One peptide. Part of a much larger renewal system.

Annotated molecular illustration of Palmitoyl Pentapeptide-4 showing its palmitoyl lipid chain and peptide sequence
Macro detail of a green leaf's veins covered in fine water droplets
06The Complete Formula

Every System,
Integrated.

Here is how it all fits together. The DMS membrane is the foundation. Five ceramides, cholesterol and phytosphingosine support the barrier. Retinal drives visible renewal. Ascorbyl Tetraisopalmitate provides oil-soluble vitamin C. Palmitoyl Pentapeptide-4 adds anti-ageing support.

Niacinamide, ectoin and natural moisturising factors support hydration and barrier function. Vitamin E, EGCG and rosemary provide additional antioxidant protection. Jojoba, grape seed, sunflower and shea nourish and soften the skin. All of them sit inside one membrane-based formula.

SEISUI is not a cream with actives added to it.

It was built as one system from the start.

A single white iris with delicate green veins on a pale background
Discover SEISUI

Biomimetic Barrier
Night Cream

50 ml